Abstract: By taking the energy efficiency as the objective function, a nonlinear programming problem with nonlinear constraints is studied under the constraints of time delay and transmission power. That is to say, a kind of new power-resource allocation algorithm (PAA) with interference restraining based on FBMC-OQAM (filter bank multicarrier-offset quadrature amplitude modulation) has been presented in this paper, which can improve the energy efficiency of entire network resource and protect small-cell user (SU) in the network from too much interference while virtual queue is used to transform the extra packet delay caused by the contention for channel of multi-user into the queuing delay in the virtual queue. An iterative algorithm for PAA to solve the problem is used. The fractional objective function is transformed into polynomial form, and the global optimal solution is obtained by iteration after reducing the computational complexity. At the same time, a sub-optimal method is developed to reduce computational complexity and some performance. The simulation results show that the optimal algorithm has higher performance and the sub-optimal method has lower computational complexity. The designed algorithm has important value for the practical applications, such as the Internet of things, Internet of vehicles, signal processing, artificial intelligence, and so on. Now, it has been used in our project on cognitive radio network (CRN) to solve the problem of power resource allocation.