Abstract: Constructing a software and hardware system-level prototype platform for accelerating data center services requires the consideration of factors such as high computing power, scalability, flexibility, and low cost. To enhance data center capabilities, research from the perspective of software-hardware synergy has been conducted on the innovation of heterogeneous computing in cloud platform architecture, hardware implementation, high-speed interconnection, and applications. A reconfigurable and combinable software-hardware acceleration prototype system is designed and built to simplify existing processor-centric system-level computing platform construction methods, enabling rapid deployment and system-level prototype validation of target software-hardware designs. To achieve these objectives, methods such as decoupled reconfigurable architecture device virtualization and remote mapping are utilized to uncover the potential of independent computing units. An ISOF (independent system of FPGA) software-hardware computing platform system is constructed to surpass the capabilities of conventional server designs, enabling low-cost and efficient expansion of computing units while allowing clients to flexibly utilize peripheral resources. To address system-level communication challenges, a communication hardware platform and interaction mechanism between computing units are designed. Additionally, to enhance the agility of the software-hardware system-level platform, ISOF provides a flexible and unified invocation interface. Finally, through the analysis and evaluation of the system-level objectives of the platform, it has been verified that the platform meets the current computing and acceleration requirements, ensuring high-speed, low-latency communication, as well as good throughput and efficient elastic scalability. In addition, improvements have been made in congestion avoidance and packet recovery mechanisms based on high-speed communication, meeting the stability requirements of communication at data center scale.