Abstract: With the growing popularity of positioning devices and other localization schemes, greedy geographical routing protocols have received extensive attention due to their substantial advantages compared to topology based routing protocols. But, lots of data packets are dropped for the phenomenon of temporary communication blindness resulted from fixed period beacon exchange in greedy geographical routing protocols in mobile sensor networks. Based on the right hand rule, the face routing that doesn’t cognized the character of void and transfers the data along the long route path sometimes, thus, the delay of data packets is prolonged. In the paper, a new real-time and reliable greedy geographical routing protocol is proposed. It adopts a new adaptive beacon exchange algorithm and buffer zone based forwarding strategy to eliminate the phenomenon of temporary communication blindness, and adopts a route signs based adaptive void-handle algorithm to mitigating inefficiency in recent greedy geographical routing. Simulation results show that the protocol can acquire high packet success delivery ratio and lower delivery delay for significantly eliminating the phenomenon of temporary communication blindness and by pass the routing void efficiently, especially introducing no more overhead. So the protocol is scalable and applicable to large-scale mobile wireless sensor networks that require high real-time and reliability performance.