Abstract: It is well known that VLSI will serve as a basis for the haradware of the fifth-generation computer systems.But how can VLSI play the role well and completely? In this paper,by presenting some results in the field of VLSI structure research(e.g.the efficient pipeline processor array for the matrix multiplication,universal parallel computation models,VLSI lexical analyzer,VLSI sorting circuits,etc.),we have discussed the general characteristics and the potentiality for practical application of VLSI structure research,and explored the importance in the development of the fifth-generation computer systems.